Pharmacogenomics in Aspirin Intolerance
نویسندگان
چکیده
منابع مشابه
Salicylate Food Intolerance and Aspirin Hypersensitivity in Nasal Polyposis
Background: A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). Objective: To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. Methods: A cross sectional multicenter study was d...
متن کاملSurgical treatment of nasal polyposis in patients with aspirin intolerance.
It is not fully understood why humans possess paranasal sinuses and for many years there has been speculation as to their physiological significance. Much the same uncertainty holds true for the pathophysiology of chronic paranasal sinusitis, a disease which represents a major therapeutic challenge despite recent medical and surgical progress. 3 There are probably several distinct subtypes of c...
متن کاملSalicylate Food Intolerance and Aspirin Hypersensitivity in Nasal Polyposis.
BACKGROUND A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). OBJECTIVE To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. METHODS A cross sectional multicenter study was done...
متن کاملPlatelet kinetics in asthmatic patients with and without aspirin intolerance.
BACKGROUND A reduced platelet survival time has been described in asthmatic patients. There is also good evidence that platelets are involved in aspirin induced asthma. Since aspirin intolerant patients usually suffer from an active disease and often require anti-inflammatory treatment, it has been suggested that platelet survival time may be shorter in aspirin intolerant asthmatic subjects tha...
متن کاملWhat do we know about the genetics of aspirin intolerance?
Although acetylsalicylic acid is prescribed for a broad range of diseases, it can induce a wide array of clinically recognized hypersensitivity reactions, including aspirin-intolerant asthma (AIA) with rhinitis and aspirin-intolerant urticaria (AIU) with anaphylaxis. Altered eicosanoid metabolism is the generally accepted mechanism of aspirin intolerance; the overproduction of cysteinyl leucotr...
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ژورنال
عنوان ژورنال: Current Drug Metabolism
سال: 2009
ISSN: 1389-2002
DOI: 10.2174/138920009790711814